GLRB Antikörper (N-Term)

Produktnummer ABIN5536519

Produktdetails anti-GLRB Antikörper

Target: GLRB (Glycine Receptor, beta (GLRB))

Bindungsspezifität: AA 103-132, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GLRB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This GLRB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 103-132 amino acids from the N-terminal region of human GLRB.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu GLRB

Target: GLRB (Glycine Receptor, beta (GLRB))

Andere Bezeichnung: GLRB (GLRB Produkte)

Synonyme: HKPX2 antikoerper, glrb antikoerper, MGC145156 antikoerper, AI853901 antikoerper, Glyrb antikoerper, spa antikoerper, spastic antikoerper, glrb2 antikoerper, zgc:101041 antikoerper, glycine receptor beta antikoerper, glycine receptor, beta antikoerper, glycine receptor, beta subunit antikoerper, glycine receptor, beta b antikoerper, GLRB antikoerper, Glrb antikoerper, glrb antikoerper, glrbb antikoerper

Hintergrund: This gene encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants.

Molekulargewicht: 56 kDa

Gen-ID: 2743

UniProt: P48167