ERI2 Antikörper (AA 444-472)

Produktnummer ABIN5536072

Der Kaninchen Polyklonal anti-ERI2 Antikörper (ABIN5536072) detektiert spezifisch ERI2 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für ERI2 Antikörper (AA 444-472) (ABIN5536072)

Target: ERI2 (EXOD1) (ERI1 Exoribonuclease Family Member 2 (EXOD1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ERI2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ERI2 Antikörper

Bindungsspezifität: AA 444-472

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ERI2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 444-472 amino acids from the Central region of human ERI2.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu ERI2

Target: ERI2 (EXOD1) (ERI1 Exoribonuclease Family Member 2 (EXOD1))

Andere Bezeichnung: ERI2

Hintergrund: EXOD1 (Exonuclease domain-containing protein 1), also known as ERI2 (ERI1 exoribonuclease 2), is a 691 amino acid protein that contains one exonuclease domain, which catalyzes the hydrolysis of unpaired or mismatched nucleotides. EXOD1 acitivity is dependent on the binding of two magnesium ions per subunit. There are four isoforms of EXOD1 that are produced as a result of alternative splicing events. The gene encoding EXOD1 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3 % of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.

Molekulargewicht: 77 kDa

Gen-ID: 112479

UniProt: A8K979