TRH Antikörper (AA 209-238)

Produktnummer ABIN5535020

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TRH in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für TRH Antikörper (AA 209-238) (ABIN5535020)

Target: TRH (Thyrotropin-Releasing Hormone (TRH))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TRH Antikörper

Bindungsspezifität: AA 209-238

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TRHR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 209-238 amino acids from the Central region of human TRHR.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.35 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu TRH

Target: TRH (Thyrotropin-Releasing Hormone (TRH))

Andere Bezeichnung: TRH

Hintergrund: Thyrotropin-releasing hormone (TRH, MIM 275120), a small neuropeptide, is widely distributed throughout the central and peripheral nervous system as well as in extraneural tissues. The peptide is synthesized in the hypothalamus and transported by the portal vascular system to the anterior pituitary where it acts on thyrotropic and lactotropic cells to promote secretion of TSH and prolactin, respectively. Thyrotropin-releasing hormone receptor is a G protein-coupled receptor that activates the inositol phospholipid-calcium-protein kinase C transduction pathway upon the binding of TRH. The TRHR gene is expressed in the thyrotrope cells of the anterior pituitary.

Molekulargewicht: 45 kDa

Gen-ID: 7201

UniProt: P34981

Pathways: Positive Regulation of Peptide Hormone Secretion, Feeding Behaviour