MRGPRX2 Antikörper (C-Term)

Produktnummer ABIN5533062

Der Kaninchen Polyklonal Anti-MRGPRX2-Antikörper wurde für WB validiert. Er ist geeignet, MRGPRX2 in Proben von Human zu detektieren.

Kurzübersicht für MRGPRX2 Antikörper (C-Term) (ABIN5533062)

Target: MRGPRX2 (G Protein-Coupled Receptor MRGX2 (MRGPRX2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MRGPRX2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MRGPRX2 Antikörper

Bindungsspezifität: AA 287-315, C-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MRGPRX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 287-315 amino acids from the C-terminal region of human MRGPRX2.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu MRGPRX2

Target: MRGPRX2 (G Protein-Coupled Receptor MRGX2 (MRGPRX2))

Andere Bezeichnung: MRGPRX2

Hintergrund: MRGPRX2 is the orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Cortistatin-14 seems to be a high potency ligand at this receptor. Cortistatin has several biological functions including roles in sleep regulation locomotor activity, and cortical function. In receptor-expressing cells, cortistatin-stimulated increases in intracellular Ca(2+) but had no effect on basal or forskolin-stimulated cAMP levels, suggesting that this receptor is G(q)-coupled.

Molekulargewicht: 37 kDa

Gen-ID: 117194

UniProt: Q96LB1