Apelin Antikörper (AA 215-244)

Produktnummer ABIN5532824

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Apelin in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Apelin Antikörper (AA 215-244) (ABIN5532824)

Target: Apelin (APLN)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Apelin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Apelin Antikörper

Bindungsspezifität: AA 215-244

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This APLNR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 215-244 amino acids from the Central region of human APLNR.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu Apelin

Target: Apelin (APLN)

Andere Bezeichnung: APLN

Hintergrund: This gene encodes a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified.

Molekulargewicht: 43 kDa

Gen-ID: 187

UniProt: P35414

Pathways: Positive Regulation of Peptide Hormone Secretion, Hormone Activity, Feeding Behaviour