SORD Antikörper (AA 211-239)

Produktnummer ABIN5532181

Dieses Anti-SORD-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SORD in WB. Geeignet für Human.

Kurzübersicht für SORD Antikörper (AA 211-239) (ABIN5532181)

Target: SORD (Sorbitol Dehydrogenase (SORD))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SORD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SORD Antikörper

Bindungsspezifität: AA 211-239

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SORD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 211-239 amino acids from the Central region of human SORD.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu SORD

Target: SORD (Sorbitol Dehydrogenase (SORD))

Andere Bezeichnung: SORD

Hintergrund: Sorbitol dehydrogenase (SORD, EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1, MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.

Molekulargewicht: 38 kDa

Gen-ID: 6652

UniProt: Q00796