RNF34 Antikörper (C-Term)

Produktnummer ABIN5532049

Dieses Anti-RNF34-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von RNF34 in WB. Geeignet für Human.

Kurzübersicht für RNF34 Antikörper (C-Term) (ABIN5532049)

Target: RNF34 (Ring Finger Protein 34 (RNF34))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RNF34 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RNF34 Antikörper

Bindungsspezifität: AA 283-311, C-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RNF34 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 283-311 amino acids from the C-terminal region of human RNF34.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu RNF34

Target: RNF34 (Ring Finger Protein 34 (RNF34))

Andere Bezeichnung: RNF34

Hintergrund: The protein encoded by this gene contains a RINF finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein interacts with DNAJA3/hTid-1, which is a DnaJ protein reported to function as a modulator of apoptosis. Overexpression of this gene in Hela cells was shown to confer the resistance to TNF-alpha induced apoptosis, suggesting an anti-apoptotic function of this protein. This protein can be cleaved by caspase-3 during the induction of apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Molekulargewicht: 42 kDa

Gen-ID: 80196

UniProt: Q969K3