QPRT Antikörper (C-Term)

Produktnummer ABIN5531984

Produktdetails anti-QPRT Antikörper

Target: QPRT (Quinolinate Phosphoribosyltransferase (QPRT))

Bindungsspezifität: AA 206-234, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser QPRT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This QPRT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 206-234 amino acids from the C-terminal region of human QPRT.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu QPRT

Target: QPRT (Quinolinate Phosphoribosyltransferase (QPRT))

Andere Bezeichnung: QPRT (QPRT Produkte)

Synonyme: ECK0108 antikoerper, JW0105 antikoerper, VF2184 antikoerper, QPRTase antikoerper, 2410027J01Rik antikoerper, AI647766 antikoerper, quinolinate phosphoribosyltransferase antikoerper, nicotinate-nucleotide pyrophosphorylase antikoerper, nicotinate-nucleotide diphosphorylase antikoerper, carboxylating antikoerper, ECs0113 antikoerper, nadC antikoerper, VP2522 antikoerper, STY0167 antikoerper, BJE04_RS13210 antikoerper, QPRT antikoerper, Qprt antikoerper

Hintergrund: This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease.

Molekulargewicht: 31 kDa

Gen-ID: 23475

UniProt: Q15274