MXI1 Antikörper (AA 53-82)

Produktnummer ABIN5531570

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch MXI1 in WB. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für MXI1 Antikörper (AA 53-82) (ABIN5531570)

Target: MXI1 (MAX Interactor 1 (MXI1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MXI1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MXI1 Antikörper

Bindungsspezifität: AA 53-82

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MXI1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 53-82 amino acids from the Central region of human MXI1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu MXI1

Target: MXI1 (MAX Interactor 1 (MXI1))

Andere Bezeichnung: MXI1

Hintergrund: Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally.

Molekulargewicht: 26 kDa

Gen-ID: 4601

UniProt: P50539

Pathways: Maintenance of Protein Location