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GRM7 Antikörper (C-Term)

GRM7 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5531275
  • Target Alle GRM7 Antikörper anzeigen
    GRM7 (Glutamate Receptor, Metabotropic 7 (GRM7))
    Bindungsspezifität
    • 15
    • 8
    • 7
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 857-887, C-Term
    Reaktivität
    • 51
    • 20
    • 16
    • 9
    • 8
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 42
    • 11
    • 1
    Kaninchen
    Klonalität
    • 43
    • 11
    Polyklonal
    Konjugat
    • 37
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GRM7 Antikörper ist unkonjugiert
    Applikation
    • 42
    • 24
    • 12
    • 9
    • 8
    • 7
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
    Immunogen
    This Metabotropic Glutamate Receptor 7 (GPRC1G) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 857-887 amino acids from the C-terminal region of human Metabotropic Glutamate Receptor 7 (GPRC1G).
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product GRM7 Primärantikörper
  • Applikationshinweise
    For WB starting dilution is: 1:1000

    For IHC-P starting dilution is: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    2 mg/mL
    Buffer
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    GRM7 (Glutamate Receptor, Metabotropic 7 (GRM7))
    Andere Bezeichnung
    Metabotropic Glutamate Receptor 7 (GRM7 Produkte)
    Synonyme
    MGLUR7 antikoerper, GLUR7 antikoerper, GPRC1G antikoerper, MGLU7 antikoerper, 6330570A01Rik antikoerper, BB176677 antikoerper, C030018L03 antikoerper, E130018M02Rik antikoerper, Gpr1g antikoerper, Gprc1g antikoerper, mGluR7 antikoerper, glutamate metabotropic receptor 7 antikoerper, glutamate receptor, metabotropic 7 antikoerper, GRM7 antikoerper, Grm7 antikoerper
    Hintergrund
    L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Alternative splice variants of GRM8 have been described but their full-length nature has not been determined.
    Molekulargewicht
    102 kDa
    Gen-ID
    2917
    UniProt
    Q14831
    Pathways
    Sensory Perception of Sound, cAMP Metabolic Process, Feeding Behaviour
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