WFDC2 Antikörper (AA 31-168)
Kurzübersicht für WFDC2 Antikörper (AA 31-168) (ABIN5519074)
Target
Alle WFDC2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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    - 
                                            Bindungsspezifität
- AA 31-168
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                                            Verwendungszweck
- Anti-HE4/Wfdc2 Antibody Picoband®
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                                            Kreuzreaktivität (Details)
- No cross-reactivity with other proteins.
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                                            Produktmerkmale
- Anti-HE4/Wfdc2 Antibody Picoband® (ABIN5519074). Tested in IHC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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                                            Aufreinigung
- Immunogen affinity purified.
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                                            Immunogen
- E. coli-derived rat HE4 recombinant protein (Position: E31-F168).
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                                            Isotyp
- IgG
 
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    - 
                                            Applikationshinweise
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                        Western blot, 0.1-0.5 μg/mL
 Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
 ELISA (Cap), 1-5 μg/mL
 1. "Entrez Gene: WFDC2 WAP four-disulfide core domain 2". 2. Hellström I, Raycraft J, Hayden-Ledbetter M, Ledbetter JA, Schummer M, McIntosh M, Drescher C, Urban N, Hellström KE (2003-07-01). "The HE4 (WFDC2) Protein Is a Biomarker for Ovarian Carcinoma". Cancer Research63 (13): 3695-3700. 3. Molina R, Escudero JM, Augé JM, Filella X, Foj L, Torné A, Lejarcegui J, Pahisa J (2011). "HE4 a novel tumour marker for ovarian cancer: Comparison with CA 125 and ROMA algorithm in patients with gynaecological diseases". Tumor Biology 32 (6): 1087-95.
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                                            Kommentare
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                        We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P). 
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                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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    - 
                                            Format
- Lyophilized
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                                            Rekonstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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                                            Konzentration
- 500 μg/mL
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                                            Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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                                            Konservierungsmittel
- Sodium azide
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                                            Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            Lagerung
- 4 °C,-20 °C
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                                            Informationen zur Lagerung
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                        Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. 
 It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
 
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    - WFDC2 (WAP Four-Disulfide Core Domain 2 (WFDC2))
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                                            Andere Bezeichnung
- Wfdc2
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                                            Hintergrund
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                        Synonyms: WAP four-disulfide core domain protein 2, Epididymal secretory protein 4, RE4, Wfdc2, Tissue Specificity: Highly expressed in epithelial tissues, particularly those of the gastrointestinal and respiratory tracts, such as large intestine and trachea, followed by kidney, small intestine, appendix and stomach. Background: WAP four-disulfide core domain protein 2, also known as Human Epididymis Protein 4 (HE4), is a protein that in humans is encoded by the WFDC2 gene. This gene encodes a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation. 
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                                            Molekulargewicht
- 19 kDa
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                                            Gen-ID
- 286888
 Target
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