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TFF3 Antikörper (AA 23-81)

Dieses Anti-TFF3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TFF3 in WB, IHC und ELISA. Geeignet für Maus und Ratte.
Produktnummer ABIN5519063

Kurzübersicht für TFF3 Antikörper (AA 23-81) (ABIN5519063)

Target

Alle TFF3 Antikörper anzeigen
TFF3 (Trefoil Factor 3 (Intestinal) (TFF3))

Reaktivität

  • 64
  • 30
  • 28
  • 11
  • 7
  • 3
Maus, Ratte

Wirt

  • 87
  • 18
  • 1
Kaninchen

Klonalität

  • 85
  • 21
Polyklonal

Konjugat

  • 53
  • 22
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser TFF3 Antikörper ist unkonjugiert

Applikation

  • 82
  • 54
  • 38
  • 32
  • 25
  • 15
  • 13
  • 13
  • 9
  • 8
  • 6
  • 5
  • 3
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • Bindungsspezifität

    • 16
    • 11
    • 11
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 23-81

    Verwendungszweck

    Anti-TFF3 Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins.

    Produktmerkmale

    Anti-TFF3 Antibody Picoband® (ABIN5519063). Tested in ELISA, IHC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E. coli-derived rat TFF3 recombinant protein (Position: Q23-F81).

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.1-0.5 μg/mL
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
    ELISA, 0.1-0.5 μg/mL
    1. Paulsen, F. P., Woon, C.-W., Varoga, D., Jansen, A., Garreis, F., Jager, K., Amm, M., Podolsky, D. K., Steven, P., Barker, N. P., Sel, S. Intestinal trefoil factor/TFF3 promotes re-epithelialization of corneal wounds. J. Biol. Chem. 283: 13418-13427, 2008. 2. Schmitt, H., Wundrack, I., Beck, S., Gott, P., Welter, C., Shizuya, H., Simon, M. I., Blin, N. A third P-domain peptide gene (TFF3), human intestinal trefoil factor, maps to 21q22.3. Cytogenet. Cell Genet. 72: 299-302, 1996.

    Kommentare

    We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target

    TFF3 (Trefoil Factor 3 (Intestinal) (TFF3))

    Andere Bezeichnung

    Tff3

    Hintergrund

    Synonyms: Trefoil factor 3, Intestinal trefoil factor, rITF, Polypeptide P1.B, rP1.B, Tff3, Itf,

    Tissue Specificity: Expressed in goblet cells of the intestines, and colon, in paraventricular hypothalamus and supraoptic nuclei. Weakly expressed in gastric epithelial cells (at protein level). Expressed by goblet cells of small and large intestinal epithelia, kidney and stomach. Expressed in the paraventricular hypothalamus, arcuate nucleus and amygdala of the brain. Weakly expressed in gastric epithelial cells.

    Background: Trefoil factor 3 is a protein that in humans is encoded by the TFF3 gene. It is mapped to 21q22.3. Members of the trefoil family can interact with mucins and have an influence on mucus viscosity. They also promote migration of epithelial cells, are linked to antiapoptosis, induce cell scattering, trigger chemotaxis, and participate in immune responses. This gene is a marker of columnar epithelium and is expressed in a variety of tissues including goblet cells of the intestines and colon. It has been found that TFF3 is the most highly upregulated gene in 19 poorly differentiated endometrioid endometrial carcinomas (G3-EECs) compared with normal endometrium biopsies.

    Molekulargewicht

    12 kDa

    Gen-ID

    25563

    UniProt

    Q03191
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