MED14 Antikörper (AA 181-375)

Produktnummer ABIN5519034

Produktdetails anti-MED14 Antikörper

Target: MED14 (Mediator Complex Subunit 14 (MED14))

Bindungsspezifität: AA 181-375

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MED14 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Verwendungszweck: Rabbit IgG polyclonal antibody for MED14 detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for MED14 detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.
Gene Name: mediator complex subunit 14
Protein Name: Mediator of RNA polymerase II transcription subunit 14

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived huamn MED14 recombinant protein (Position: D181-D375).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu MED14

Target: MED14 (Mediator Complex Subunit 14 (MED14))

Andere Bezeichnung: MED14 (MED14 Produkte)

Synonyme: CG12031 antikoerper, Dmel\\CG12031 antikoerper, Med14 antikoerper, Trap170 antikoerper, dTRAP170 antikoerper, p160 antikoerper, EXLM1 antikoerper, crsp150 antikoerper, crsp2 antikoerper, trap170 antikoerper, wu:fd21c05 antikoerper, wu:fk28h11 antikoerper, CRSP2 antikoerper, NV18605 antikoerper, CRSP150 antikoerper, CSRP antikoerper, CXorf4 antikoerper, DRIP150 antikoerper, RGR1 antikoerper, TRAP170 antikoerper, 9930001L01Rik antikoerper, AU041628 antikoerper, Crsp2 antikoerper, ENSMUSG00000073278 antikoerper, Gm641 antikoerper, ORF1 antikoerper, RGD1560170 antikoerper, Mediator complex subunit 14 antikoerper, mediator complex subunit 14 antikoerper, mediator of RNA polymerase II transcription subunit 14 antikoerper, transcriptional regulation antikoerper, MED14 antikoerper, med14 antikoerper, LOC100113592 antikoerper, Med14 antikoerper, RGR1 antikoerper

Hintergrund: Mediator of RNA polymerase II transcription subunit 14 is an enzyme that in humans is encoded by the MED14 gene. The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein contains a bipartite nuclear localization signal. This gene is known to escape chromosome X-inactivation.

Synonyms: Mediator of RNA polymerase II transcription subunit 14, Activator-recruited cofactor 150 kDa component, ARC150, Cofactor required for Sp1 transcriptional activation subunit 2, CRSP complex subunit 2, Mediator complex subunit 14, RGR1 homolog, hRGR1, Thyroid hormone receptor-associated protein complex 170 kDa component, Trap170, Transcriptional coactivator CRSP150, Vitamin D3 receptor-interacting protein complex 150 kDa component, DRIP150, MED14, ARC150, CRSP2, CXorf4, DRIP150, EXLM1, RGR1, TRAP170

Gen-ID: 9282

UniProt: O60244

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha