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GSTP1 Antikörper (AA 2-210)

Der Kaninchen Polyklonal Anti-GSTP1-Antikörper wurde für WB, IHC und ELISA validiert. Er ist geeignet, GSTP1 in Proben von Human, Maus und Ratte zu detektieren. Es sind 3+ Publikationen verfügbar.
Produktnummer ABIN5518996

Kurzübersicht für GSTP1 Antikörper (AA 2-210) (ABIN5518996)

Target

Alle GSTP1 Antikörper anzeigen
GSTP1 (Glutathione S-Transferase pi 1 (GSTP1))

Reaktivität

  • 123
  • 63
  • 54
  • 13
  • 7
  • 5
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 132
  • 43
  • 1
Kaninchen

Klonalität

  • 118
  • 59
Polyklonal

Konjugat

  • 102
  • 22
  • 20
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser GSTP1 Antikörper ist unkonjugiert

Applikation

  • 147
  • 85
  • 52
  • 45
  • 41
  • 27
  • 25
  • 17
  • 14
  • 14
  • 8
  • 7
  • 5
  • 5
  • 3
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • Bindungsspezifität

    • 40
    • 19
    • 16
    • 8
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2-210

    Verwendungszweck

    Anti-GST3/GST pi/Gstp1 Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins.

    Produktmerkmale

    Anti-GST3/GST pi/Gstp1 Antibody Picoband® (ABIN5518996). Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E. coli-derived mouse GST3 / GST pi recombinant protein (Position: P2-Q210).

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.1-0.5 μg/mL
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
    ELISA, 0.1-0.5 μg/mL
    1. Bora PS, Bora NS, Wu XL, Lange LG (Oct 1991). "Molecular cloning, sequencing, and expression of human myocardial fatty acid ethyl ester synthase-III cDNA". J Biol Chem 266 (25): 16774-7. 2. Morrow, C. S., Cowan, K. H., Goldsmith, M. E. : Structure of the human genomic glutathione S-transferase-pi gene. Gene 75: 3-11, 1989. 3. Smith CM, Bora PS, Bora NS, Jones C, Gerhard DS (Nov 1995). "Genetic and radiation-reduced somatic cell hybrid sublocalization of the human GSTP1 gene". Cytogenet Cell Genet 71 (3): 235-9.

    Kommentare

    We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Zhang, Yan, Xu, Fang, Zhang, Zhang, Wu, Kong, Huang: "The recovery trajectory of adolescent social defeat stress-induced behavioral, (1)H-MRS metabolites and myelin changes in Balb/c mice." in: Scientific reports, Vol. 6, pp. 27906, (2018) (PubMed).

    Sun, Hu, Xiong, Tu, Zhao, Chen, Song, Ye: "Enhanced expression of stem cell markers and drug resistance in sphere-forming non-small cell lung cancer cells." in: International journal of clinical and experimental pathology, Vol. 8, Issue 6, pp. 6287-300, (2016) (PubMed).

    Yang, Gao, Zhang, Fang, Wu, Xu, Huang: "Changes in proinflammatory cytokines and white matter in chronically stressed rats." in: Neuropsychiatric disease and treatment, Vol. 11, pp. 597-607, (2015) (PubMed).

  • Target

    GSTP1 (Glutathione S-Transferase pi 1 (GSTP1))

    Andere Bezeichnung

    Gstp1

    Hintergrund

    Synonyms: Glutathione S-transferase P 1, Gst P1, 2.5.1.18, GST YF-YF, GST class-pi, GST-piB, Preadipocyte growth factor, Gstp1, Gstpib,

    Tissue Specificity: Ubiquitously expressed.

    Background: Glutathione S-transferases pi (GSTP1), also known as GST3, is an enzyme that in humans is encoded by the GSTP1 gene. This gene is mapped to 11q13.2. GSTP1 has 7 exons and 6 introns contained within approximately 2.8 kilobases. GSTP1 belongs to Glutathione S-transferases (GSTs) which are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. GSTP1 presents in all tissues and cells, with the exception of red cells, in which only erythrocyte GST (GSTe) is observed. What's more, GSTP1 is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases.

    Molekulargewicht

    23 kDa

    Gen-ID

    14870

    UniProt

    P19157

    Pathways

    Cellular Response to Molecule of Bacterial Origin
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