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PREB Antikörper (AA 42-236)

Der Kaninchen Polyklonal Anti-PREB-Antikörper wurde für WB validiert. Er ist geeignet, PREB in Proben von Human zu detektieren.
Produktnummer ABIN5518945

Kurzübersicht für PREB Antikörper (AA 42-236) (ABIN5518945)

Target

Alle PREB Antikörper anzeigen
PREB (Prolactin Regulatory Element Binding (PREB))

Reaktivität

  • 16
  • 5
  • 5
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
Human

Wirt

  • 15
  • 1
Kaninchen

Klonalität

  • 14
  • 2
Polyklonal

Konjugat

  • 12
  • 2
  • 1
  • 1
Dieser PREB Antikörper ist unkonjugiert

Applikation

  • 12
  • 10
  • 9
  • 2
  • 1
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 7
    • 3
    • 1
    • 1
    • 1
    AA 42-236

    Verwendungszweck

    Anti-PREB Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins.

    Produktmerkmale

    Anti-PREB Antibody Picoband® (ABIN5518945). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E. coli-derived human PREB recombinant protein (Position: K42-N236). Human PREB shares 87.7% amino acid (aa) sequence identity with both mouse and rat PREB.

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.1-0.5 μg/mL, Human
    1. Edgar AJ (Jul 2003). "The gene structure and expression of human ABHD1: overlapping polyadenylation signal sequence with Sec12". BMC Genomics. 4: 18. 2. Fliss MS, Hinkle PM, Bancroft C (May 1999). "Expression cloning and characterization of PREB (prolactin regulatory element binding), a novel WD motif DNA-binding protein with a capacity to regulate prolactin promoter activity". MolEndocrinol. 13 (4): 644-657.

    Kommentare

    We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target

    PREB (Prolactin Regulatory Element Binding (PREB))

    Andere Bezeichnung

    PREB

    Hintergrund

    Synonyms: Prolactin regulatory element-binding protein,Mammalian guanine nucleotide exchange factor mSec12,PREB,SEC12,

    Tissue Specificity: Ubiquitous. .

    Background: Prolactin regulatory element-binding protein is a protein that in humans is encoded by the PREB gene. This gene encodes a protein that specifically binds to a Pit1-binding element of the prolactin (PRL) promoter. This protein may act as a transcriptional regulator and is thought to be involved in some of the developmental abnormalities observed in patients with partial trisomy 2p. This gene overlaps the abhydrolase domain containing 1 (ABHD1) gene on the opposite strand.

    Molekulargewicht

    45 kDa

    Gen-ID

    10113

    Pathways

    ER-Nucleus Signaling
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