IL17RA Antikörper (AA 53-284)

Produktnummer ABIN5518928

Dieses Anti-IL17RA-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von IL17RA in WB und ELISA. Geeignet für Human.

Kurzübersicht für IL17RA Antikörper (AA 53-284) (ABIN5518928)

Target: IL17RA (Interleukin 17 Receptor A (IL17RA))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL17RA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-IL17RA Antikörper

Bindungsspezifität: AA 53-284

Verwendungszweck: Anti-L17A Receptor/IL17RA Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-L17A Receptor/IL17RA Antibody Picoband® (ABIN5518928). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived human IL17RA recombinant protein (Position: K53-Q284). Human IL17RA shares 74.1% amino acid (aa) sequence identity with mouse IL17RA.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA, 0.1-0.5 μg/mL, -, Western blot, 0.1-0.5 μg/mL, Human,
1. "Entrez Gene: IL17RA interleukin 17 receptor A". 2. Yao, Z., Spriggs, M. K., Derry, J. M. J., Strockbine, L., Park, L. S., VandenBos, T., Zappone, J., Painter, S. L., Armitage, R. J. Molecular characterization of the human interleukin (IL)-17 receptor. Cytokine 9: 794-800, 1997. 3. Yao, Z., Fanslow, W. C., Seldin, M. F., Rousseau, A.-M., Painter, S. L., Comeau, M. R., Cohen, J. I., Spriggs, M. K. Herpesvirus saimiri encodes a new cytokine, IL-17, which binds to a novel cytokine receptor. Immunity 3: 811-821, 1995.

Kommentare:

We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu IL17RA

Target: IL17RA (Interleukin 17 Receptor A (IL17RA))

Andere Bezeichnung: IL17RA

Hintergrund:

Synonyms: Interleukin-17 receptor A,IL-17 receptor A,IL-17RA,CDw217,CD217,IL17RA,IL17R,

Tissue Specificity: Widely expressed. .

Background: Interleukin 17 receptor A, also known as IL17RA and CDw217 (cluster of differentiation w217), is a human gene. The IL17R gene is mapped to 22q11.22-q11.23 by radiation hybrid analysis. Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The protein encoded by this gene is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis.

Molekulargewicht: 120-150 kDa

Gen-ID: 23765

UniProt: Q96F46

Pathways: SARS-CoV-2 Protein Interaktom