HOXB1 Antikörper (C-Term)

Produktnummer ABIN5518919

Dieses Anti-HOXB1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von HOXB1 in WB. Geeignet für Human, Maus und Ratte.

Kurzübersicht für HOXB1 Antikörper (C-Term) (ABIN5518919)

Target: HOXB1 (Homeobox B1 (HOXB1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HOXB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-HOXB1 Antikörper

Bindungsspezifität: AA 176-220, C-Term

Verwendungszweck: Anti-HOXB1 Antibody Picoband®

Sequenz: TARTFDWMKV KRNPPKTAKV SEPGLGSPSG LRTNFTTRQL TELEK

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-HOXB1 Antibody Picoband® (ABIN5518919). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human HOXB1, different from the related mouse sequence by four amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. Iimura, T., Pourquie, O. Collinear activation of Hoxb genes during gastrulation is linked to mesoderm cell ingression. Nature 442: 568-571, 2006. 2. Goddard, J. M., Rossel, M., Manley, N. R., Capecchi, M. R. Mice with targeted disruption of Hoxb-1 fail to form the motor nucleus of the VIIth nerve. Development 122: 3217-3228, 1996. 3. Webb, B. D., Shaaban, S., Gaspar, H., Cunha, L. F., Schubert, C. R., Hao, K., Robson, C. D., Chan, W.-M., Andrews, C., MacKinnon, S., Oystreck, D. T., Hunter, D. G., Iacovelli, A. J., Ye, X., Camminady, A., Engle, E. C., Jabs, E. W. HOXB1 founder mutation in humans recapitulates the phenotype of Hoxb1-/- mice. Am. J. Hum. Genet. 91: 171-179, 2012.

Kommentare:

We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu HOXB1

Target: HOXB1 (Homeobox B1 (HOXB1))

Andere Bezeichnung: HOXB1

Hintergrund:

Synonyms: Homeobox protein Hox-B1,Homeobox protein Hox-2I,HOXB1,HOX2I,

Background: Homeobox protein Hox-B1 is a protein that in humans is encoded by the HOXB1 gene. This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXB genes located in a cluster on chromosome 17.

Molekulargewicht: 32 kDa

Gen-ID: 3211

UniProt: P14653