DLG3 Antikörper (AA 749-817)

Produktnummer ABIN5518907

Dieses Anti-DLG3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von DLG3 in WB und IHC. Geeignet für Human, Ratte und Maus.

Kurzübersicht für DLG3 Antikörper (AA 749-817) (ABIN5518907)

Target: DLG3 (Discs, Large Homolog 3 (DLG3))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DLG3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-DLG3 Antikörper

Bindungsspezifität: AA 749-817

Verwendungszweck: Anti-SAP102/DLG3 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-S/DLG3 Antibody Picoband® (ABIN5518907). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived human SAP102 recombinant protein (Position: E749-L817). Human SAP102 shares 98.6% amino acid (aa) sequence identity with both mouse and rat SAP102.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse, Rat, Human Western blot, 0.1-0.5 μg/mL, Mouse, Rat, Human,
1. Stathakis DG, Lee D, Bryant PJ (Aug 1998). "DLG3, the gene encoding human neuroendocrine Dlg (NE-Dlg), is located within the 1.8-Mb dystonia-parkinsonism region at Xq13.1". Genomics. 49 (2): 310-3. 2. "Entrez Gene: DLG3 Discs, large homolog 3 (neuroendocrine-dlg, Drosophila)".

Kommentare:

We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu DLG3

Target: DLG3 (Discs, Large Homolog 3 (DLG3))

Andere Bezeichnung: DLG3

Hintergrund:

Synonyms: Disks large homolog 3,Neuroendocrine-DLG,Synapse-associated protein 102,SAP-102,SAP102,XLMR,DLG3,KIAA1232,

Tissue Specificity: Mainly expressed in testis. Isoform 3 is expressed predominantly in adult testis, weakly in pancreas, embryonic testis and sperm, and at very low levels in other organs.

Background: Disks large homolog 3 (DLG3) also known as neuroendocrine-DLG or synapse-associated protein 102 (SAP-102) is a protein that in humans is encoded by the DLG3 gene. DLG3 is a member of the membrane-associated guanylate kinase (MAGUK) superfamily of proteins. The encoded protein may play a role in clustering of NMDA receptors at excitatory synapses. It may also negatively regulate cell proliferation through interaction with the C-terminal region of the adenomatosis polyposis coli tumor suppressor protein. Mutations in this gene have been associated with X-linked mental retardation.

Molekulargewicht: 102 kDa

Gen-ID: 1741

UniProt: Q92796