ATOH1 Antikörper (N-Term)

Produktnummer ABIN5518893

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ATOH1 in WB. Er zeigt eine Reaktivität gegenüber Human und Ratte.

Kurzübersicht für ATOH1 Antikörper (N-Term) (ABIN5518893)

Target: ATOH1 (Atonal Homolog 1 (Drosophila) (ATOH1))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATOH1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ATOH1 Antikörper

Bindungsspezifität: AA 1-30, N-Term

Verwendungszweck: Anti-MATH1/HATH1/ATOH1 Antibody Picoband®

Sequenz: MSRLLHAEEW AEVKELGDHH RQPQPHHLPQ

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-MATH1/HATH1/ATOH1 Antibody Picoband® (ABIN5518893). Tested in WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human MATH1/HATH1, different from the related mouse sequence by three amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL, Human, Rat
1. Ben-Arie N, McCall AE, Berkman S, Eichele G, Bellen HJ, Zoghbi HY (Sep 1996). "Evolutionary conservation of sequence and expression of the bHLH protein Atonal suggests a conserved role in neurogenesis". Human Molecular Genetics. 5 (9): 1207-16. 2. "Entrez Gene: ATOH1 atonal homolog 1 (Drosophila)".

Kommentare:

We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu ATOH1

Target: ATOH1 (Atonal Homolog 1 (Drosophila) (ATOH1))

Andere Bezeichnung: ATOH1

Hintergrund:

Synonyms: Protein atonal homolog 1,Class A basic helix-loop-helix protein 14,bHLHa14,Helix-loop-helix protein hATH-1,hATH1,ATOH1,ATH1, BHLHA14,

Tissue Specificity: Retina.

Background: Protein atonal homolog 1 is a protein that in humans is encoded by the ATOH1 gene. This protein belongs to the basic helix-loop-helix (BHLH) family of transcription factors. It activates E-box dependent transcription along with E47. ATOH1 is required for the formation of both neural and non-neural cell types. Using genetic deletion in mice, Atoh1 has been shown to be essential for formation of cerebellar granule neurons, inner ear hair cells, spinal cord interneurons, Merkel cells of the skin, and intestinal secretory cells (goblet, enteroendocrine, and Paneth cells).

Molekulargewicht: 38 kDa

Gen-ID: 474

UniProt: Q92858