Annexin IV Antikörper (Middle Region)

Produktnummer ABIN5518805

Dieses Anti-Annexin IV-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Annexin IV in WB, IHC und FACS. Geeignet für Human, Ratte und Maus. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für Annexin IV Antikörper (Middle Region) (ABIN5518805)

Target: Annexin IV (ANXA4) (Annexin A4 (ANXA4))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Annexin IV Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Produktdetails anti-Annexin IV Antikörper

Bindungsspezifität: AA 119-152, Middle Region

Verwendungszweck: Anti-Annexin IV/ANXA4 Antibody Picoband®

Sequenz: EEIRRISQTY QQQYGRSLED DIRSDTSFMF QRVL

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-Annexin IV/ANXA4 Antibody Picoband® (ABIN5518805). Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human Annexin IV, different from the related mouse and rat sequences by three amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
1. Barrow, L. L., Simin, K., Jones, J. M., Lee, D. C., Meisler, M. H. Conserved linkage of early growth response 4, annexin 4, and transforming growth factor alpha on mouse chromosome 6. Genomics 19: 388-390, 1994. 2. Fukuoka, S.-I., Kern, H., Kazuki-Sugino, R., Ikeda, Y. Cloning and characterization of ZAP36, an annexin-like, zymogen granule membrane associated protein, in exocrine pancreas. Biochim. Biophys. Acta 1575: 148-152, 2002. 3. Tait, J. F., Smith, C., Frankenberry, D. A., Miao, C. H., Adler, D. A., Disteche, C. M. Chromosomal mapping of the human annexin IV (ANX4) gene. Genomics 12: 313-318, 1992.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Referenzen für anti-Annexin IV Antikörper (ABIN5518805)

Manville, Abbott: "Ancient and modern anticonvulsants act synergistically in a KCNQ potassium channel binding pocket." in: Nature communications, Vol. 9, Issue 1, pp. 3845, (2018) (PubMed).

Details zu Annexin IV

Target: Annexin IV (ANXA4) (Annexin A4 (ANXA4))

Andere Bezeichnung: ANXA4

Hintergrund:

Synonyms: Annexin A4,35-beta calcimedin,Annexin IV,Annexin-4,Carbohydrate-binding protein p33/p41,Chromobindin-4,Endonexin I,Lipocortin IV,P32.5,PP4-X,Placental anticoagulant protein II,PAP-II,Protein II,ANXA4,ANX4,

Tissue Specificity: Expressed at high levels in lung, placenta and thymus and at lower levels in ovary, intestine and brain.

Background: ANXA4 (Annexin A4), also known as ANX4, is a protein that in humans is encoded by the ANXA4 gene. It belongs to the annexin family of calcium-dependent phospholipid binding proteins. By PCR analysis of somatic cell hybrids and in situ hybridization with a cDNA probe, the human ANXA4 gene is mapped to chromosome 2p13. Isolated from human placenta, ANXA4 encodes a protein that has possible interactions with ATP, and has in vitro anticoagulant activity and also inhibits phospholipase A2 activity. And ANXA4 is almost exclusively expressed in epithelial cells.

Molekulargewicht: 36 kDa

Gen-ID: 307

UniProt: P09525