HBV Large S Protein Antikörper (N-Term)

Produktnummer ABIN5518758

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch HBV Large S Protein in WB und IHC. Er zeigt eine Reaktivität gegenüber Human und wurde in 4+ Publikationen erwähnt.

Kurzübersicht für HBV Large S Protein Antikörper (N-Term) (ABIN5518758)

Target: HBV Large S Protein (L-HBsAG) (Hepatitis B Virus Large Surface Protein (L-HBsAG))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HBV Large S Protein Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-HBV Large S Protein Antikörper

Bindungsspezifität: AA 4-51, N-Term

Verwendungszweck: Anti-Hepatitis B Virus Antibody Picoband®

Sequenz: WSSKPRQGMG TNLSVPNPLG FFPDHQLDPA FGANSNNPDW DFNPNKDQ

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Produktmerkmale: Rabbit IgG polyclonal antibody for Large S protein(S) detection. Tested with WB, IHC-P in Human,HBV.
Gene Name: long surface protein, PreS1, L protein, LHBs, large S protein, pre-S1/pre-S2/S regions, L glycoprotein, L-HBsAG, LHBs
Protein Name: Large S protein

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human Hepatitis B Virus.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Western blot, 0.1-0.5 μg/mL, HBV
1. Magnius LO, Norder H (1995). "Subtypes, genotypes and molecular epidemiology of the hepatitis B virus as reflected by sequence variability of the S-gene". Intervirology. 38 (1-2): 24-34. 2. Rysgaard, Carolyn D, Morris, Cory S, Drees, Denny, Bebber, Tami, Davis, Scott R, Kulhavy, Jeff, Krasowski, Matthew D (2012). "Positive hepatitis B surface antigen tests due to recent vaccination: a persistent problem". BMC Clinical Pathology. 12 (1): 15. doi:10.1186/1472-6890-12-15. Retrieved11 March 2014.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Referenzen für anti-HBV Large S Protein Antikörper (ABIN5518758)

Xiangji, Feng, Qingbao, Weifeng, Xiaoqing, Baihe, Feng, Hongyang, Mengchao: "Knockdown of HBV surface antigen gene expression by a lentiviral microRNA-based system inhibits HBV replication and HCC growth." in: Journal of viral hepatitis, Vol. 18, Issue 9, pp. 653-60, (2011) (PubMed).

Zhang, Wang, Li, Qiao: "Expression of transforming growth factor-alpha and hepatitis B surface antigen in human hepatocellular carcinoma tissues and its significance." in: World journal of gastroenterology, Vol. 10, Issue 6, pp. 830-3, (2004) (PubMed).

Paliaga, Braga: "Passive limitation of adduction after Cüppers's 'Fadenoperation' on medial recti." in: The British journal of ophthalmology, Vol. 73, Issue 8, pp. 633-5, (1989) (PubMed).

Ramsey: "Should medicine today be taught without medical ethics?" in: Connecticut medicine, Vol. 37, Issue 8, pp. 420-1, (1973) (PubMed).

Details zu HBV Large S Protein

Target: HBV Large S Protein (L-HBsAG) (Hepatitis B Virus Large Surface Protein (L-HBsAG))

Andere Bezeichnung: S

Substanzklasse: Viral Protein

Hintergrund:

Synonyms: Large S protein ,S ,

Tissue Specificity: Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.

Background: Hepatitis B virus, abbreviated HBV, is a species of the genus Orthohepadnavirus, which is likewise a part of the Hepadnaviridae family of viruses. This virus causes the disease hepatitis B. It consists of HBsAg, HBcAg (HBeAg is a splice variant), Hepatitis B virus DNA polymerase and HBx. Among these, HBsAg (also known as the Australia antigen) is the surface antigen of the hepatitis B virus (HBV). It indicates current hepatitis B infection. The viral envelope of an enveloped virus has different surface proteins from the rest of the virus which act as antigens. These antigens are recognized by antibody proteins that bind specifically to one of these surface proteins.

Molekulargewicht: 6 kDa

UniProt: D2X4M3