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HBV Large S Protein Antikörper (N-Term)

L-HBsAG Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5518758
  • Target Alle HBV Large S Protein (L-HBsAG) Produkte
    HBV Large S Protein (L-HBsAG) (Hepatitis B Virus Large Surface Protein (L-HBsAG))
    Bindungsspezifität
    AA 4-51, N-Term
    Reaktivität
    Human
    Wirt
    • 16
    Kaninchen
    Klonalität
    • 16
    Polyklonal
    Konjugat
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser HBV Large S Protein Antikörper ist unkonjugiert
    Applikation
    • 16
    • 13
    • 13
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Verwendungszweck
    Anti-Hepatitis B Virus Antibody Picoband®
    Sequenz
    WSSKPRQGMG TNLSVPNPLG FFPDHQLDPA FGANSNNPDW DFNPNKDQ
    Kreuzreaktivität (Details)
    No cross-reactivity with other proteins
    Produktmerkmale
    Rabbit IgG polyclonal antibody for Large S protein(S) detection. Tested with WB, IHC-P in Human,HBV.
    Gene Name: long surface protein, PreS1, L protein, LHBs, large S protein, pre-S1/pre-S2/S regions, L glycoprotein, L-HBsAG, LHBs
    Protein Name: Large S protein
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence at the N-terminus of human Hepatitis B Virus.
    Isotyp
    IgG
  • Applikationshinweise
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
    Western blot, 0.1-0.5 μg/mL, HBV
    1. Magnius LO, Norder H (1995). "Subtypes, genotypes and molecular epidemiology of the hepatitis B virus as reflected by sequence variability of the S-gene". Intervirology. 38 (1-2): 24-34. 2. Rysgaard, Carolyn D, Morris, Cory S, Drees, Denny, Bebber, Tami, Davis, Scott R, Kulhavy, Jeff, Krasowski, Matthew D (2012). "Positive hepatitis B surface antigen tests due to recent vaccination: a persistent problem". BMC Clinical Pathology. 12 (1): 15. doi:10.1186/1472-6890-12-15. Retrieved11 March 2014.
    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Xiangji, Feng, Qingbao, Weifeng, Xiaoqing, Baihe, Feng, Hongyang, Mengchao: "Knockdown of HBV surface antigen gene expression by a lentiviral microRNA-based system inhibits HBV replication and HCC growth." in: Journal of viral hepatitis, Vol. 18, Issue 9, pp. 653-60, (2011) (PubMed).

    Zhang, Wang, Li, Qiao: "Expression of transforming growth factor-alpha and hepatitis B surface antigen in human hepatocellular carcinoma tissues and its significance." in: World journal of gastroenterology, Vol. 10, Issue 6, pp. 830-3, (2004) (PubMed).

    Paliaga, Braga: "Passive limitation of adduction after Cüppers's 'Fadenoperation' on medial recti." in: The British journal of ophthalmology, Vol. 73, Issue 8, pp. 633-5, (1989) (PubMed).

    Ramsey: "Should medicine today be taught without medical ethics?" in: Connecticut medicine, Vol. 37, Issue 8, pp. 420-1, (1973) (PubMed).

  • Target
    HBV Large S Protein (L-HBsAG) (Hepatitis B Virus Large Surface Protein (L-HBsAG))
    Andere Bezeichnung
    S (L-HBsAG Produkte)
    Substanzklasse
    Viral Protein
    Hintergrund

    Synonyms: Large S protein ,S ,

    Tissue Specificity: Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.

    Background: Hepatitis B virus, abbreviated HBV, is a species of the genus Orthohepadnavirus, which is likewise a part of the Hepadnaviridae family of viruses. This virus causes the disease hepatitis B. It consists of HBsAg, HBcAg (HBeAg is a splice variant), Hepatitis B virus DNA polymerase and HBx. Among these, HBsAg (also known as the Australia antigen) is the surface antigen of the hepatitis B virus (HBV). It indicates current hepatitis B infection. The viral envelope of an enveloped virus has different surface proteins from the rest of the virus which act as antigens. These antigens are recognized by antibody proteins that bind specifically to one of these surface proteins.

    Molekulargewicht
    6 kDa
    UniProt
    D2X4M3
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