CKAP4 Antikörper (N-Term)

Produktnummer ABIN5518750

Der Kaninchen Polyklonal Anti-CKAP4-Antikörper wurde für WB validiert. Er ist geeignet, CKAP4 in Proben von Maus zu detektieren.

Kurzübersicht für CKAP4 Antikörper (N-Term) (ABIN5518750)

Target: CKAP4 (Cytoskeleton-Associated Protein 4 (CKAP4))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CKAP4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CKAP4 Antikörper

Bindungsspezifität: AA 95-118, N-Term

Verwendungszweck: Anti-CKAP4 Antibody Picoband®

Sequenz: LVAAAAFSGW YVHHVLEEVQ QVRR

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-CKAP4 Antibody Picoband® (ABIN5518750). Tested in WB applications. This antibody reacts with Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of mouse CKAP4, different from the related human sequence by one amino acid.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL, Mouse
1. "Entrez Gene: CKAP4 cytoskeleton-associated protein 4". 2. Schweizer A, Rohrer J, Jeno P, DeMaio A, Buchman TG, Hauri HP (Jul 1993). "A reversibly palmitoylated resident protein (p63) of an ER-Golgi intermediate compartment is related to a circulatory shock resuscitation protein". J Cell Sci. 104 (3): 685-94.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu CKAP4

Target: CKAP4 (Cytoskeleton-Associated Protein 4 (CKAP4))

Andere Bezeichnung: Ckap4

Hintergrund:

Synonyms: Cytoskeleton-associated protein 4,63- kDa cytoskeleton-linking membrane protein,Climp-63,p63,Ckap4,

Tissue Specificity: High in intestine and in peripheral blood mononuclear cells, low in lung, kidney, thymus, uterus, vasculature and brain. Not found in liver, heart, retina oe skeletal muscle.

Background: Cytoskeleton-associated protein 4, also known as CLIMP63 and p63, is a protein that in humans is encoded by the CKAP4 gene. It is mapped to 12q23.3. CKAP4 is found on the plasma membrane of select cells such as vascular smooth muscle and Type II Greater alveolar lung cells. It has a bimodal distribution. First, CKAP4 is found on the plasma membrane and serves as a receptor for SP-A/surfactant protein-A (in lung) and tPA (in vessels). Second, it is embedded in the membrane of a compartment that links the ER with the Golgi apparatus. This localization is dependent on its ability to form homooligomers, and its presence serves to anchor microtubules and the formation of tubular ER.

Molekulargewicht: 66 kDa

Gen-ID: 216197