ANGPTL2 Antikörper (Middle Region)

Produktnummer ABIN5518733

Dieses Anti-ANGPTL2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ANGPTL2 in WB und IHC. Geeignet für Human, Maus und Ratte.

Kurzübersicht für ANGPTL2 Antikörper (Middle Region) (ABIN5518733)

Target: ANGPTL2 (Angiopoietin-Like 2 (ANGPTL2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ANGPTL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-ANGPTL2 Antikörper

Bindungsspezifität: AA 275-312, Middle Region

Verwendungszweck: Anti-ANGPTL2 Antibody Picoband®

Sequenz: WRDCLQALED GHDTSSIYLV KPENTNRLMQ VWCDQRHD

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Produktmerkmale: Anti-ANGPTL2 Antibody Picoband® (ABIN5518733). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human ANGPTL2, different from the related mouse sequence by one amino acid.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
Western blot, 0.1-0.5 μg/mL, Mouse, Rat, Human
1. "Entrez Gene: ANGPTL2 angiopoietin-like 2". 2. Kim I, Moon SO, Koh KN, Kim H, Uhm CS, Kwak HJ, Kim NG, Koh GY (Oct 1999). "Molecular cloning, expression, and characterization of angiopoietin-related protein. angiopoietin-related protein induces endothelial cell sprouting". J Biol Chem. 274 (37): 26523-8. 3. Sun H, Zheng JM, Chen S, et al. (2007). "Enhanced expression of ANGPTL2 in the microvascular lesions of diabetic glomerulopathy". Nephron Exp. Nephrol.105 (4): e117-23.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu ANGPTL2

Target: ANGPTL2 (Angiopoietin-Like 2 (ANGPTL2))

Andere Bezeichnung: ANGPTL2

Hintergrund:

Synonyms: Angiopoietin-related protein 2,Angiopoietin-like protein 2,ANGPTL2,ARP2,UNQ170/PRO196,

Tissue Specificity: Widely expressed in heart, small intestine, spleen and stomach. Also found in lower levels in colon, ovary, adrenal gland, skeletal muscle and in prostate.

Background: Angiopoietin-related protein 2, also known as angiopoietin-like protein 2, is a protein that in humans is encoded by the ANGPTL2 gene. Angiopoietins are members of the vascular endothelial growth factor family and the only known growth factors largely specific for vascular endothelium. Angiopoietin-1, angiopoietin-2, and angiopoietin-4 participate in the formation of blood vessels. ANGPTL2 protein is a secreted glycoprotein with homology to the angiopoietins and may exert a function on endothelial cells through autocrine or paracrine action.

Molekulargewicht: 57 kDa

Gen-ID: 23452