AKAP2 Antikörper (C-Term)

Produktnummer ABIN5518729

Der Kaninchen Polyklonal Anti-AKAP2-Antikörper wurde für WB validiert. Er ist geeignet, AKAP2 in Proben von Human und Maus zu detektieren.

Kurzübersicht für AKAP2 Antikörper (C-Term) (ABIN5518729)

Target: AKAP2 (A Kinase (PRKA) Anchor Protein 2 (AKAP2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AKAP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-AKAP2 Antikörper

Bindungsspezifität: AA 813-852, C-Term

Verwendungszweck: Anti-AKAP2 Antibody Picoband®

Sequenz: ETHKSKRRER MDDSSVLEAT RVNRRKSALA LRWEAGIYAN

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-AKAP2 Antibody Picoband® (ABIN5518729). Tested in WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human AKAP2, identical to the related mouse and rat sequences.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL, Human, Mouse
1. "Entrez Gene: AKAP2 A kinase (PRKA) anchor protein 2". 2. Alto NM, Soderling SH, Hoshi N, Langeberg LK, Fayos R, Jennings PA, Scott JD (Apr 2003). "Bioinformatic design of A-kinase anchoring protein-in silico: a potent and selective peptide antagonist of type II protein kinase A anchoring". Proc. Natl. Acad. Sci. U.S.A. 100 (8): 4445-50. 3. Dong F, Feldmesser M, Casadevall A, Rubin CS (Mar 1998). "Molecular characterization of a cDNA that encodes six isoforms of a novel murine A kinase anchor protein". J. Biol. Chem. 273 (11): 6533-41.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu AKAP2

Target: AKAP2 (A Kinase (PRKA) Anchor Protein 2 (AKAP2))

Andere Bezeichnung: AKAP2

Hintergrund:

Synonyms: A-kinase anchor protein 2,AKAP-2,AKAP-KL,Protein kinase A-anchoring protein 2,PRKA2,AKAP2,KIAA0920, PRKA2,

Tissue Specificity: Expressed in fetal skin, spleen and tonsil. Expressed mostly in the basal epithelia of skin and in proliferating B-cells of the tonsil.

Background: A-kinase anchor protein 2 is an enzyme that in humans is encoded by the AKAP2 gene. It is mapped to 9q31.3. The protein encoded by this gene binds to the regulatory subunit of protein kinase A and is found associated with the actin cytoskeleton. The encoded protein mediates signals carried by cAMP and may be involved in creating polarity in certain signaling processes. Three transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 150-170 kDa

Gen-ID: 11217

UniProt: Q9Y2D5