C11ORF80 Antikörper (C-Term)
Kurzübersicht für C11ORF80 Antikörper (C-Term) (ABIN5518072)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Verwendungszweck
- C11ORF80 Antibody - C-terminal region
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Sequenz
- KVFREITQHQ FLHHCSCEVK QLTLEKKDSA QGTEDAPDNS SLELLADTSG
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Homologie
- Human: 100%, Rat: 83%
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Aufreinigung
- Affinity purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human C11ORF80
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP68096-100UG
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- prevent freeze-thaw cycles
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- C11ORF80 (Chromosome 11 Open Reading Frame 80 (C11ORF80))
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Andere Bezeichnung
- C11ORF80
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Hintergrund
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Background Information: Isoform 3: Component of a topoisomerase 6 complex specifically required for meiotic recombination. Together with SPO11, mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination. The complex promotes relaxation of negative and positive supercoiled DNA and DNA decatenation through cleavage and ligation cycles.
Gene Name: chromosome 11 open reading frame 80
Alternative Symbols: HYDM4, TOP6BL, TOPOVIBL
Protein Name: Type 2 DNA topoisomerase 6 subunit B-like
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Molekulargewicht
- 53 kDa
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Gen-ID
- 79703
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UniProt
- Q8N6T0
Target
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