DENND3 Antikörper (C-Term)
Kurzübersicht für DENND3 Antikörper (C-Term) (ABIN5518005)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- C-Term
-
Verwendungszweck
- DENND3 Antibody - C-terminal region
-
Sequenz
- INCMIRVKKQ VWVGSRGLGQ GTPKGKIYVI DAERKTVEKE LVAHMDTVRT
-
Produktmerkmale
- This is a rabbit polyclonal antibody against DENND3. It was validated on Western Blot.
-
Aufreinigung
- Affinity Purified
-
Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human DENND3
-
-
-
-
Applikationshinweise
- Optimal working dilution should be determined by the investigator.
-
Kommentare
-
We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP68268-100UG
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 0.5 mg/mL
-
Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handhabung
- prevent freeze-thaw cycles
-
Lagerung
- 4 °C,-20 °C
-
Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
-
- DENND3 (DENN/MADD Domain Containing 3 (DENND3))
-
Andere Bezeichnung
- DENND3
-
Hintergrund
-
Background Information: DENND3 is a guanine nucleotide exchange factor (GEF) activating RAB12. It promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB12 into its active GTP-bound form. Thereby, DENND3 may play a role in protein transport from recycling endosomes to lysosomes regulating, for instance, the degradation of the transferrin receptor.
Alternative Symbols: DENND3, KIAA0870,
-
Molekulargewicht
- 126kDa
-
Gen-ID
- 22898
-
NCBI Accession
- NP_055772
-
UniProt
- A2RUS2
Target
-