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DENND3 Antikörper (C-Term)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch DENND3 in WB. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN5518005

Kurzübersicht für DENND3 Antikörper (C-Term) (ABIN5518005)

Target

DENND3 (DENN/MADD Domain Containing 3 (DENND3))

Reaktivität

  • 1
  • 1
  • 1
Human

Wirt

  • 2
Kaninchen

Klonalität

  • 2
Polyklonal

Konjugat

  • 2
Dieser DENND3 Antikörper ist unkonjugiert

Applikation

  • 2
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    C-Term

    Sequenz

    INCMIRVKKQ VWVGSRGLGQ GTPKGKIYVI DAERKTVEKE LVAHMDTVRT

    Produktmerkmale

    This is a rabbit polyclonal antibody against DENND3. It was validated on Western Blot.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the C-terminal region of Human DENND3
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    DENND3 (DENN/MADD Domain Containing 3 (DENND3))

    Andere Bezeichnung

    DENND3

    Hintergrund

    DENND3 is a guanine nucleotide exchange factor (GEF) activating RAB12. It promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB12 into its active GTP-bound form. Thereby, DENND3 may play a role in protein transport from recycling endosomes to lysosomes regulating, for instance, the degradation of the transferrin receptor.

    Alias Symbols: DENND3, KIAA0870,

    Protein Interaction Partner: UBC, YAP1,

    Protein Size: 1146

    Gen-ID

    22898

    NCBI Accession

    NP_055772
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