GSAP Antikörper (N-Term)

Produktnummer ABIN5517988

Der Kaninchen Polyklonal anti-GSAP Antikörper wird verwendet zum Nachweis von GSAP in Proben von Human, Ratte, Rind (Kuh), Hund, Pferd und Kaninchen. Er wurde validiert für WB.

Kurzübersicht für GSAP Antikörper (N-Term) (ABIN5517988)

Target: GSAP (PION) (Pigeon Homolog (PION))

Reaktivität: Human, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GSAP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GSAP Antikörper

Bindungsspezifität: N-Term

Sequenz: QTRQNELLYT FEKDLQVFSC SVNSERTLLA ASLVQSTKEG KRNELQPGSK

Homologie: Cow: 85%, Dog: 85%, Horse: 93%, Human: 100%, Rabbit: 93%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against GSAP. It was validated on Western Blot.

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human GSAP

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu GSAP

Target: GSAP (PION) (Pigeon Homolog (PION))

Andere Bezeichnung: GSAP

Hintergrund: Accumulation of neurotoxic amyloid-beta is a major hallmark of Alzheimer disease. Formation of amyloid-beta is catalyzed by gamma-secretase, a protease with numerous substrates. PION, or GSAP, selectively increases amyloid-beta production through a mechanism involving its interaction with both gamma-secretase and its substrate, the amyloid-beta precursor protein C-terminal fragment (APP-CTF).

Alias Symbols: GSAP, PION,

Protein Size: 854

Gen-ID: 54103

NCBI Accession: NP_059135

UniProt: A4D1B5