C16orf57 Antikörper (N-Term)

Produktnummer ABIN5517969

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch C16orf57 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für C16orf57 Antikörper (N-Term) (ABIN5517969)

Target: C16orf57 (USB1) (U6 SnRNA Biogenesis 1 (USB1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C16orf57 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-C16orf57 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: USB1 Antibody - N-terminal region

Sequenz: LVGYSSSGSE DESEDGMRTR PGDGSHRRGQ SPLPRQRFPV PDSVLNMFPG

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human C16ORF57

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP80076-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu C16orf57

Target: C16orf57 (USB1) (U6 SnRNA Biogenesis 1 (USB1))

Andere Bezeichnung: USB1

Hintergrund:

Background Information: This gene encodes a protein with several conserved domains, however, its exact function is not known. Mutations in this gene are associated with poikiloderma with neutropenia (PN), which shows phenotypic overlap with Rothmund-Thomson syndrome (RTS) caused by mutations in the RECQL4 gene. It is believed that this gene product interacts with RECQL4 protein via SMAD4 proteins, explaining the partial clinical overlap between PN and RTS. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Gene Name: U6 snRNA biogenesis phosphodiesterase 1

Alternative Symbols: PN, Mpn1, HVSL1, hUsb1, C16orf57

Protein Name: U6 snRNA phosphodiesterase

Molekulargewicht: 20 kDa

Gen-ID: 79650

NCBI Accession: NP_001182231

UniProt: Q9BQ65