C1QL3 Antikörper (Middle Region)
Kurzübersicht für C1QL3 Antikörper (Middle Region) (ABIN5517812)
Target
Alle C1QL3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Verwendungszweck
- C1QL3 Antibody - middle region
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Sequenz
- VPKIAFYAGL KRQHEGYEVL KFDDVVTNLG NHYDPTTGKF TCSIPGIYFF
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Produktmerkmale
- This is a rabbit polyclonal antibody against C1QL3. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of Human C1QL3
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP68022-100UG
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- prevent freeze-thaw cycles
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- C1QL3 (Complement Component 1, Q Subcomponent-Like 3 (C1QL3))
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Andere Bezeichnung
- C1QL3
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Hintergrund
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Background Information: C1QL3 may regulate the number of excitatory synapses that are formed on hippocampus neurons. It has no effect on inhibitory synapses . It plays a role in glucose homeostasis. Via AMPK signaling pathway, C1QL3 stimulates glucose uptake in adipocytes, myotubes and hepatocytes and enhances insulin-stimulated glucose uptake. In a hepatoma cell line, C1QL3 reduces the expression of gluconeogenic enzymes G6PC and PCK1 and hence decreases de novo glucose production.
Alternative Symbols: C1ql, K100, CTRP13, C1QTNF13
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Molekulargewicht
- 28kDa
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Gen-ID
- 389941
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NCBI Accession
- NP_001010908
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UniProt
- Q5VWW1
Target
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