CLN5 Antikörper (C-Term)

Produktnummer ABIN5517800

Der Kaninchen Polyklonal anti-CLN5 Antikörper (ABIN5517800) detektiert spezifisch CLN5. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Schwein und Kaninchen.

Kurzübersicht für CLN5 Antikörper (C-Term) (ABIN5517800)

Target: CLN5 (Ceroid-Lipofuscinosis, Neuronal 5 (CLN5))

Reaktivität: Human, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CLN5 Antikörper ist unkonjugiert

Applikation: Bitte anfragen

Produktdetails anti-CLN5 Antikörper

Bindungsspezifität: C-Term

Sequenz: DNETGIYYET WNVKASPEKG AETWFDSYDC SKFVLRTFNK LAEFGAEFKN

Homologie: Cow: 77%, Dog: 79%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Pig: 86%, Rabbit: 86%, Rat: 79%

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CLN5

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CLN5

Target: CLN5 (Ceroid-Lipofuscinosis, Neuronal 5 (CLN5))

Andere Bezeichnung: CLN5

Hintergrund: This gene is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL). Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely encode proteins involved in the degradation of post-translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function.

Alias Symbols: NCL

Protein Interaction Partner: ARHGAP36, FBXO27, SPNS1, SFXN3, SLC25A22, SEC61A1, FBXO6, PHGDH, GANAB, OS9, CDIPT, SLC25A13, CDS2, SLC25A11, XPO1, SLC25A1, SEL1L, RPN1, RCN2, HMGCS1, DBH, CLN5, CLGN, CANX, CALU, CALR, ATP2A2, ATP1A3, ARF4, SLC25A6, SLC25A5, SLC25A4, Dlg4, UBC, KRT8,

Protein Size: 358

Gen-ID: 1203

NCBI Accession: NM_006493, NP_006484

UniProt: O75503