SIM2 Antikörper (Middle Region)

Produktnummer ABIN5517795

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch SIM2 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Kaninchen, Rind (Kuh) und Schwein.

Kurzübersicht für SIM2 Antikörper (Middle Region) (ABIN5517795)

Target: SIM2 (Single-Minded Homolog 2 (SIM2))

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Kaninchen, Rind (Kuh), Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SIM2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SIM2 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: SIM2 Antibody - middle region

Sequenz: VLTEIEYKEL QLSLEQVSTA KSQDSWRTAL STSQETRKLV KPKNTKMKTK

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 91%, Pig: 93%, Rabbit: 92%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against SIM2. It was validated on Western Blot.

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human SIM2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP33297-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu SIM2

Target: SIM2 (Single-Minded Homolog 2 (SIM2))

Andere Bezeichnung: SIM2

Hintergrund:

Background Information: This gene represents a homolog of the Drosophila single-minded (sim) gene, which encodes a transcription factor that is a master regulator of neurogenesis. The encoded protein is ubiquitinated by RING-IBR-RING-type E3 ubiquitin ligases, including the parkin RBR E3 ubiquitin protein ligase. This gene maps within the so-called Down syndrome chromosomal region, and is thus thought to contribute to some specific Down syndrome phenotypes. Alternative splicing of this gene results in multiple transcript variants.

Gene Name: single-minded homolog 2 (Drosophila)

Alternative Symbols: SIM, bHLHe15, HMC13F06, HMC29C01

Protein Name: Single-minded homolog 2

Molekulargewicht: 73kDa

Gen-ID: 6493

UniProt: Q14190