SIM2 Antikörper (Middle Region)

Produktnummer ABIN5517795

Produktdetails anti-SIM2 Antikörper

Target: SIM2 (Single-Minded Homolog 2 (SIM2))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Kaninchen, Hund, Meerschweinchen, Pferd, Rind (Kuh), Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SIM2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: VLTEIEYKEL QLSLEQVSTA KSQDSWRTAL STSQETRKLV KPKNTKMKTK

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 91%, Pig: 93%, Rabbit: 92%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against SIM2. It was validated on Western Blot.

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human SIM2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SIM2

Target: SIM2 (Single-Minded Homolog 2 (SIM2))

Andere Bezeichnung: SIM2 (SIM2 Produkte)

Synonyme: Xsim2 antikoerper, sim2-A antikoerper, xSim antikoerper, HMC13F06 antikoerper, HMC29C01 antikoerper, SIM antikoerper, bHLHe15 antikoerper, single-minded family bHLH transcription factor 2 S homeolog antikoerper, single-minded family bHLH transcription factor 2 antikoerper, single-minded homolog 2 (Drosophila) antikoerper, sim2.S antikoerper, sim2 antikoerper, SIM2 antikoerper, Sim2 antikoerper

Hintergrund: This gene represents a homolog of the Drosophila single-minded (sim) gene, which encodes a transcription factor that is a master regulator of neurogenesis. The encoded protein is ubiquitinated by RING-IBR-RING-type E3 ubiquitin ligases, including the parkin RBR E3 ubiquitin protein ligase. This gene maps within the so-called Down syndrome chromosomal region, and is thus thought to contribute to some specific Down syndrome phenotypes. Alternative splicing of this gene results in multiple transcript variants.

Alias Symbols: SIM2, BHLHE15,

Protein Size: 667

Gen-ID: 6493

UniProt: Q14190