TSPYL5
Reaktivität: Maus
FACS, IF (cc), IF (p)
Wirt: Kaninchen
Polyclonal
AbBy Fluor® 680
Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target
TSPYL5
(TSPY-Like 5 (TSPYL5))
Andere Bezeichnung
TSPYL5
Hintergrund
TSPYL5 is involved in modulation of cell growth and cellular response to gamma radiation probably via regulation of the Akt signaling pathway. It is involved in regulation of p53/TP53. It suppresses p53/TP53 protein levels and promotes its ubiquitination, the function is dependent on USP7 and independent on MDM2. It is proposed to displace p53/TP53 from interaction with USP7.