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THOC7 Antikörper (C-Term)

Der Kaninchen Polyklonal Anti-THOC7-Antikörper wurde für WB validiert. Er ist geeignet, THOC7 in Proben von Human, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen und Schwein zu detektieren.
Produktnummer ABIN5517619

Kurzübersicht für THOC7 Antikörper (C-Term) (ABIN5517619)

Target

Alle THOC7 Antikörper anzeigen
THOC7 (THO Complex 7 (THOC7))

Reaktivität

  • 22
  • 13
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Human, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Schwein

Wirt

  • 22
Kaninchen

Klonalität

  • 22
Polyklonal

Konjugat

  • 11
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser THOC7 Antikörper ist unkonjugiert

Applikation

  • 10
  • 6
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    C-Term

    Sequenz

    SVEDKLELRR KQFHVLLSTI HELQQTLEND EKLSEVEEAQ EASMETDPKP

    Homologie

    Cow: 100%, Dog: 93%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Pig: 93%, Rabbit: 79%, Rat: 79%

    Produktmerkmale

    This is a rabbit polyclonal antibody against THOC7. It was validated on Western Blot.

    Aufreinigung

    Affinity purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the C-terminal region of Human THOC7
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    THOC7 (THO Complex 7 (THOC7))

    Andere Bezeichnung

    THOC7

    Hintergrund

    THOC7 is required for efficient export of polyadenylated RNA. It acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production.

    Alias Symbols: THOC7, NIF3L1BP1,

    Protein Interaction Partner: THOC2, RPA3, RPA2, RPA1, CKAP4, UBC, ZC3H15, TRMT112, PPIP5K2, THOC1, UBE3C, USP13, ZPR1, THOC5, VIM, S100A13, WDR36, ZCRB1, THOC3, ZNF606, THOC6, ALYREF, DDX39B, NIF3L1, CHD3, MED8, GOT2, MED18, MED22,

    Protein Size: 204

    Gen-ID

    80145

    NCBI Accession

    NP_079351

    UniProt

    Q6I9Y2
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