PYDC1 Antikörper (N-Term)

Produktnummer ABIN5517612

Produktdetails anti-PYDC1 Antikörper

Target: PYDC1 (PYD (Pyrin Domain) Containing 1 (PYDC1))

Bindungsspezifität: N-Term

Reaktivität: Human, Saccharomyces cerevisiae, Rind (Kuh), Hund, Ziege, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PYDC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: REAILKVLEN LTPEELKKFK MKLGTVPLRE GFERIPRGAL GQLDIVDLTD

Homologie: Cow: 83%, Dog: 83%, Goat: 83%, Guinea Pig: 85%, Horse: 83%, Human: 100%, Yeast: 77%

Produktmerkmale: This is a rabbit polyclonal antibody against PYDC1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human PYDC1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PYDC1

Target: PYDC1 (PYD (Pyrin Domain) Containing 1 (PYDC1))

Andere Bezeichnung: PYDC1 (PYDC1 Produkte)

Synonyme: ASC2 antikoerper, POP1 antikoerper, PYC1 antikoerper, pyrin domain containing 1 antikoerper, PYDC1 antikoerper

Hintergrund: PYDC1 associates with apoptosis-associated specklike protein containing a CARD domain (ASC) and modulates its ability to collaborate with pyrin and cryopyrin in NF-kappa-B and pro- caspase-1 activation. It suppresses kinase activity of NF-kappa-B inhibitor kinase (IKK) complex, expression of NF-kappa-B inducible genes and inhibits NF-kappa-B activation by cytokines and LPS.

Alias Symbols: PYDC1, ASC2, ASCI, POP1, PYC1,

Protein Interaction Partner: WDR82,

Protein Size: 89

Gen-ID: 260434

NCBI Accession: NP_690865

UniProt: Q8WXC3