PYDC1 Antikörper (N-Term)

Produktnummer ABIN5517612

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PYDC1 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Saccharomyces cerevisiae, Rind (Kuh), Hund, Ziege, Meerschweinchen und Pferd.

Kurzübersicht für PYDC1 Antikörper (N-Term) (ABIN5517612)

Target: PYDC1 (PYD (Pyrin Domain) Containing 1 (PYDC1))

Reaktivität: Human, Saccharomyces cerevisiae, Rind (Kuh), Hund, Ziege, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PYDC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PYDC1 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: PYDC1 Antibody - N-terminal region

Sequenz: REAILKVLEN LTPEELKKFK MKLGTVPLRE GFERIPRGAL GQLDIVDLTD

Homologie: Cow: 83%, Dog: 83%, Goat: 83%, Guinea Pig: 85%, Horse: 83%, Human: 100%, Yeast: 77%

Produktmerkmale: This is a rabbit polyclonal antibody against PYDC1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human PYDC1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP55560-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu PYDC1

Target: PYDC1 (PYD (Pyrin Domain) Containing 1 (PYDC1))

Andere Bezeichnung: PYDC1

Hintergrund:

Background Information: PYDC1 associates with apoptosis-associated specklike protein containing a CARD domain (ASC) and modulates its ability to collaborate with pyrin and cryopyrin in NF-kappa-B and pro- caspase-1 activation. It suppresses kinase activity of NF-kappa-B inhibitor kinase (IKK) complex, expression of NF-kappa-B inducible genes and inhibits NF-kappa-B activation by cytokines and LPS.

Gene Name: PYD (pyrin domain) containing 1

Alternative Symbols: ASC2, POP1, PYC1, cPOP1

Protein Name: Pyrin domain-containing protein 1

Molekulargewicht: 9kDa

Gen-ID: 260434

NCBI Accession: NP_690865

UniProt: Q8WXC3