Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PYDC1 in WB. Er zeigt eine Reaktivität gegenüber Human, Saccharomyces cerevisiae, Rind (Kuh), Hund, Ziege, Meerschweinchen und Pferd.
Produktnummer ABIN5517612
Kurzübersicht für PYDC1 Antikörper (N-Term) (ABIN5517612)
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target
PYDC1
(PYD (Pyrin Domain) Containing 1 (PYDC1))
Andere Bezeichnung
PYDC1
Hintergrund
PYDC1 associates with apoptosis-associated specklike protein containing a CARD domain (ASC) and modulates its ability to collaborate with pyrin and cryopyrin in NF-kappa-B and pro- caspase-1 activation. It suppresses kinase activity of NF-kappa-B inhibitor kinase (IKK) complex, expression of NF-kappa-B inducible genes and inhibits NF-kappa-B activation by cytokines and LPS.