Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch PYDC1 in WB. Er zeigt eine Reaktivität gegenüber Human, Saccharomyces cerevisiae, Rind (Kuh), Hund, Ziege, Meerschweinchen und Pferd.
Produktnummer ABIN5517612
Kurzübersicht für PYDC1 Antikörper (N-Term) (ABIN5517612)
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target
PYDC1
(PYD (Pyrin Domain) Containing 1 (PYDC1))
Andere Bezeichnung
PYDC1
Hintergrund
PYDC1 associates with apoptosis-associated specklike protein containing a CARD domain (ASC) and modulates its ability to collaborate with pyrin and cryopyrin in NF-kappa-B and pro- caspase-1 activation. It suppresses kinase activity of NF-kappa-B inhibitor kinase (IKK) complex, expression of NF-kappa-B inducible genes and inhibits NF-kappa-B activation by cytokines and LPS.