ZCCHC6 Antikörper (N-Term)

Produktnummer ABIN5517595

Der Kaninchen Polyklonal anti-ZCCHC6 Antikörper wird verwendet zum Nachweis von ZCCHC6 in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für ZCCHC6 Antikörper (N-Term) (ABIN5517595)

Target: ZCCHC6 (Zinc Finger, CCHC Domain Containing 6 (ZCCHC6))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZCCHC6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ZCCHC6 Antikörper

Bindungsspezifität: N-Term

Sequenz: SPENKKQRSR PRKPRKTRNE ENEQDGDLEG PVIDESVLST KELLGLQQAE

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ZCCHC6

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ZCCHC6

Target: ZCCHC6 (Zinc Finger, CCHC Domain Containing 6 (ZCCHC6))

Andere Bezeichnung: ZCCHC6

Hintergrund: Uridylyltransferase that mediates the terminal uridylation of mRNAs with short (less than 25 nucleotides) poly(A) tails, hence facilitating global mRNA decay. Involved in microRNA (miRNA)-induced gene silencing through uridylation of deadenylated miRNA targets. Also acts as a suppressor of miRNA biogenesis by mediating the terminal uridylation of some miRNA precursors, including that of let-7 (pre-let-7). Uridylated pre-let-7 RNA is not processed by Dicer and undergo degradation. Pre-let-7 uridylation is strongly enhanced in the presence of LIN28A. Due to functional redundancy between ZCCHC6 and ZCCHC11, the identification of the specific role of each of these proteins is difficult.

Alias Symbols: TUT7, PAPD6

Protein Size: 544

Gen-ID: 79670

NCBI Accession: NM_001185059, NP_001171988