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RASGRP1 Antikörper (Middle Region)
RASGRP1
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN5517466
Produktdetails anti-RASGRP1 Antikörper
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Target
Alle RASGRP1 Antikörper anzeigen
RASGRP1
(RAS Guanyl Releasing Protein 1 (Calcium and DAG-Regulated) (RASGRP1))
Bindungsspezifität
Alle Epitope für RASGRP1 Antikörper
Middle Region
Reaktivität
Alle Reaktivitäten für RASGRP1 Antikörper
Human
Wirt
Alle Wirte für RASGRP1 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für RASGRP1 Antikörper
Polyklonal
Konjugat
Alle Konjugate für RASGRP1 Antikörper
Dieser RASGRP1 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für RASGRP1 Antikörper
Western Blotting (WB)
Sequenz
GLCHSSISRL KETSSHVPHE INKVLGEMTE LLSSSRNYDN YRRAYGECTD
Aufreinigung
Affinity purified
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human RASGRP1
Top Product
Discover our top product RASGRP1 Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Details zu RASGRP1
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Target
RASGRP1
(RAS Guanyl Releasing Protein 1 (Calcium and DAG-Regulated) (RASGRP1))
Andere Bezeichnung
RASGRP1 (RASGRP1 Produkte )
Synonyme
Rasgrp antikoerper, CALDAG-GEFI antikoerper, CALDAG-GEFII antikoerper, RASGRP antikoerper, V antikoerper, hRasGRP1 antikoerper, RAS guanyl releasing protein 1 antikoerper, Rasgrp1 antikoerper, RASGRP1 antikoerper
Hintergrund
This gene is a member of a family of genes characterized by the presence of a Ras superfamily guanine nucleotide exchange factor (GEF) domain. It functions as a diacylglycerol (DAG)-regulated nucleotide exchange factor specifically activating Ras through the exchange of bound GDP for GTP. It activates the Erk/MAP kinase cascade and regulates T-cells and B-cells development, homeostasis and differentiation. Alternatively spliced transcript variants encoding different isoforms have been identified. Altered expression of the different isoforms of this protein may be a cause of susceptibility to systemic lupus erythematosus (SLE). Alias Symbols: V, RASGRP, hRasGRP1, CALDAG-GEFI, CALDAG-GEFII Protein Size: 797
Gen-ID
10125
NCBI Accession
NM_001128602 , NP_001122074
UniProt
O95267
Pathways
T-Zell Rezeptor Signalweg , Fc-epsilon Rezeptor Signalübertragung
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