TXNDC12 Antikörper (N-Term)

Produktnummer ABIN5517454

Der Kaninchen Polyklonal anti-TXNDC12 Antikörper wird verwendet zum Nachweis von TXNDC12 in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für TXNDC12 Antikörper (N-Term) (ABIN5517454)

Target: TXNDC12 (Thioredoxin Domain Containing 12 (Endoplasmic Reticulum) (TXNDC12))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TXNDC12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TXNDC12 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: TXNDC12 Antibody - N-terminal region

Sequenz: METRPRLGAT CLLGFSFLLL VISSDGHNGL GKGFGDHIHW RTLEDGKKEA

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TXNDC12

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP78544-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu TXNDC12

Target: TXNDC12 (Thioredoxin Domain Containing 12 (Endoplasmic Reticulum) (TXNDC12))

Andere Bezeichnung: TXNDC12

Hintergrund:

Background Information: This gene encodes a member of the thioredoxin superfamily. Members of this family are characterized by a conserved active motif called the thioredoxin fold that catalyzes disulfide bond formation and isomerization. This protein localizes to the endoplasmic reticulum and has a single atypical active motif. The encoded protein is mainly involved in catalyzing native disulfide bond formation and displays activity similar to protein-disulfide isomerases. This protein may play a role in defense against endoplasmic reticulum stress. Alternate splicing results in both coding and non-coding variants.

Gene Name: thioredoxin domain containing 12 (endoplasmic reticulum)

Alternative Symbols: AG1, AGR1, ERP16, ERP18, ERP19, TLP19, hAG-1, PDIA16, hTLP19

Protein Name: thioredoxin domain-containing protein 12

Molekulargewicht: 18 kDa

Gen-ID: 51060

NCBI Accession: NP_056997

UniProt: O95881

Pathways: Cell RedoxHomeostasis