NFKBIL2 Antikörper (C-Term)

Produktnummer ABIN5517400

Der Kaninchen Polyklonal anti-NFKBIL2 Antikörper wird verwendet zum Nachweis von NFKBIL2 in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für NFKBIL2 Antikörper (C-Term) (ABIN5517400)

Target: NFKBIL2 (Tonsoku-Like, DNA Repair Protein (NFKBIL2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NFKBIL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-NFKBIL2 Antikörper

Bindungsspezifität: C-Term

Sequenz: LTRSRRPRPR GTGDNRRPSS TSGSDSEESR PRARAKQVRL TCMQSCSAPV

Produktmerkmale: This is a rabbit polyclonal antibody against TONSL. It was validated on Western Blot.

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human TONSL

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu NFKBIL2

Target: NFKBIL2 (Tonsoku-Like, DNA Repair Protein (NFKBIL2))

Andere Bezeichnung: TONSL

Hintergrund: The protein encoded by this gene is thought to be a negative regulator of NF-kappa-B mediated transcription. The encoded protein may bind NF-kappa-B complexes and trap them in the cytoplasm, preventing them from entering the nucleus and interacting with the DNA. Phosphorylation of this protein targets it for degradation by the ubiquitination pathway, which frees the NF-kappa-B complexes to enter the nucleus.

Alias Symbols: TONSL, IKBR, NFKBIL2,

Protein Interaction Partner: HIST3H3, MCM6, MCM2, MMS22L, ASF1B, ASF1A, UBC, MYC, MAU2, SLC25A5, SUPT16H, SUGT1, AIFM1, HIST1H2BL, XRCC5, SSRP1, SLC25A3, TONSL, MCM4, HIST1H2AE, HIST1H1B, HIST1H1C, XRCC6, GSK3B, MCM7, MCM5, MCM3, EWSR1,

Protein Size: 1378

Gen-ID: 4796

NCBI Accession: NP_038460

UniProt: Q96HA7

Pathways: Maintenance of Protein Location