UBXN8 Antikörper (Middle Region)

Produktnummer ABIN5517391

Produktdetails anti-UBXN8 Antikörper

Target: UBXN8 (UBX Domain Protein 8 (UBXN8))

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UBXN8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: RKLEERFYQM TGEAWKLSSG HKLGGDEGTS QTSFETSNRE AAKSQNLPKP

Produktmerkmale: This is a rabbit polyclonal antibody against UBXN8. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human UBXN8

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu UBXN8

Target: UBXN8 (UBX Domain Protein 8 (UBXN8))

Andere Bezeichnung: UBXN8 (UBXN8 Produkte)

Synonyme: D8S2298E antikoerper, REP8 antikoerper, UBXD6 antikoerper, D0H8S2298E antikoerper, Rep-8 antikoerper, Rep8h antikoerper, Ubxd6 antikoerper, UBX domain protein 8 antikoerper, UBXN8 antikoerper, Ubxn8 antikoerper

Hintergrund: P97 or VCP (valosin-containing protein) is a versatile ATPase complex, and many cofactors are required for the p97 functional diversity. This gene encodes one of the p97 cofactors. This cofactor is a transmembrane protein and localized in the endoplasmic reticulum (ER) membrane. It tethers p97 to the ER membrane via its UBX domain. The association of this cofactor with p97 facilitates efficient ER-associated degradation of misfolded proteins. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alias Symbols: UBXN8, D8S2298E, REP8, UBXD6,

Protein Interaction Partner: UBC, ADRB2, SYVN1, VCP, VCPIP1, NPLOC4, UFD1L,

Protein Size: 270

Gen-ID: 7993

NCBI Accession: NP_005662

UniProt: O00124

Pathways: SARS-CoV-2 Protein Interaktom