PHC3 Antikörper (C-Term)

Produktnummer ABIN5517248

Der Kaninchen Polyklonal anti-PHC3 Antikörper (ABIN5517248) detektiert spezifisch PHC3 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für PHC3 Antikörper (C-Term) (ABIN5517248)

Target: PHC3 (Polyhomeotic Homolog 3 (PHC3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PHC3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PHC3 Antikörper

Bindungsspezifität: C-Term

Sequenz: LSRWNRKPDN QSLGHRGRRP SGPDGAAREH ILRQLPITYP SAEEDLASHE

Produktmerkmale: This is a rabbit polyclonal antibody against PHC3. It was validated on Western Blot.

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human PHC3

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PHC3

Target: PHC3 (Polyhomeotic Homolog 3 (PHC3))

Andere Bezeichnung: PHC3

Hintergrund: PHC3 is a component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.

Alias Symbols: PHC3, EDR3, PH3,

Protein Interaction Partner: OGT, UBC, EED, RNF2, BMI1, SOX2, ALB, CBX2, PHC3, CBX8, CBX6, SCMH1, CBX4, PCGF2, SCML1, RING1, PHC2, PHC1, SUMO2,

Protein Size: 983

Gen-ID: 80012

NCBI Accession: XP_005247847

UniProt: Q8NDX5