TRIM63 Antikörper (C-Term)
Kurzübersicht für TRIM63 Antikörper (C-Term) (ABIN5517180)
Target
Alle TRIM63 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Verwendungszweck
- TRIM63 Antibody - C-terminal region
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Sequenz
- TIITQLEDSR RVTKENSHQV KEELSQKFDT LYAILDEKKS ELLQRITQEQ
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Homologie
- Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against TRIM63. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human TRIM63
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP43364-100UG
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- prevent freeze-thaw cycles
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- TRIM63 (Tripartite Motif Containing 63 (TRIM63))
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Andere Bezeichnung
- TRIM63
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Hintergrund
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Background Information: This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is an E3 ubiquitin ligase that localizes to the Z-line and M-line lattices of myofibrils. This protein plays an important role in the atrophy of skeletal and cardiac muscle and is required for the degradation of myosin heavy chain proteins, myosin light chain, myosin binding protein, and for muscle-type creatine kinase.
Gene Name: tripartite motif containing 63, E3 ubiquitin protein ligase
Alternative Symbols: IRF, SMRZ, MURF1, MURF2, RNF28
Protein Name: E3 ubiquitin-protein ligase TRIM63
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Molekulargewicht
- 38kDa
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Gen-ID
- 84676
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NCBI Accession
- NP_115977
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UniProt
- Q969Q1
Target
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