MBNL2 Antikörper (N-Term)

Produktnummer ABIN5517157

Der Kaninchen Polyklonal anti-MBNL2 Antikörper wird verwendet zum Nachweis von MBNL2 in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für MBNL2 Antikörper (N-Term) (ABIN5517157)

Target: MBNL2 (Muscleblind-Like 2 (MBNL2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MBNL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MBNL2 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: MBNL2 Antibody - N-terminal region

Sequenz: CRQFQRGTCS RSDEECKFAH PPKSCQVENG RVIACFDSLK GRCSRENCKY

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MBNL2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP74636-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu MBNL2

Target: MBNL2 (Muscleblind-Like 2 (MBNL2))

Andere Bezeichnung: MBNL2

Hintergrund:

Background Information: This gene is a member of the muscleblind protein family which was initially described in Drosophila melanogaster. This gene encodes a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined.

Gene Name: muscleblind like splicing regulator 2

Alternative Symbols: MBLL, MBLL39, PRO2032

Protein Name: muscleblind-like protein 2

Molekulargewicht: 40 kDa

Gen-ID: 10150

NCBI Accession: NP_001292999

UniProt: Q5VZF2