NAGLU Antikörper (N-Term)
Kurzübersicht für NAGLU Antikörper (N-Term) (ABIN5517087)
Target
Alle NAGLU Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- GVLLLAGAGG AAGDEAREAA AVRALVARLL GPGPAADFSV SVERALAAKP
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Homologie
- Cow: 83%, Dog: 92%, Human: 100%, Pig: 79%
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Produktmerkmale
- This is a rabbit polyclonal antibody against ANAG. It was validated on Western Blot.
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Aufreinigung
- Affinity purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human NAGLU
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- NAGLU (N-Acetylglucosaminidase, alpha (NAGLU))
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Andere Bezeichnung
- NAGLU
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Hintergrund
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This gene encodes an enzyme that degrades heparan sulfate by hydrolysis of terminal N-acetyl-D-glucosamine residues in N-acetyl-alpha-D-glucosaminides. Defects in this gene are the cause of mucopolysaccharidosis type IIIB (MPS-IIIB), also known as Sanfilippo syndrome B. This disease is characterized by the lysosomal accumulation and urinary excretion of heparan sulfate.
Alias Symbols: NAGLU, UFHSD1,
Protein Interaction Partner: UBC, FBXO6,
Protein Size: 743 -
Gen-ID
- 4669
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NCBI Accession
- NP_000254
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UniProt
- P54802
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Pathways
- Glycosaminoglycan Metabolic Process
Target
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