NAGLU Antikörper (N-Term)

Produktnummer ABIN5517087

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch NAGLU in WB. Es zeigt Reaktivität gegenüber Proben von Human, Rind (Kuh), Hund und Schwein.

Kurzübersicht für NAGLU Antikörper (N-Term) (ABIN5517087)

Target: NAGLU (N-Acetylglucosaminidase, alpha (NAGLU))

Reaktivität: Human, Rind (Kuh), Hund, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NAGLU Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-NAGLU Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: NAGLU Antibody - N-terminal region

Sequenz: GVLLLAGAGG AAGDEAREAA AVRALVARLL GPGPAADFSV SVERALAAKP

Homologie: Cow: 83%, Dog: 92%, Human: 100%, Pig: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against ANAG. It was validated on Western Blot.

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human NAGLU

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP58644-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu NAGLU

Target: NAGLU (N-Acetylglucosaminidase, alpha (NAGLU))

Andere Bezeichnung: NAGLU

Hintergrund:

Background Information: This gene encodes an enzyme that degrades heparan sulfate by hydrolysis of terminal N-acetyl-D-glucosamine residues in N-acetyl-alpha-D-glucosaminides. Defects in this gene are the cause of mucopolysaccharidosis type IIIB (MPS-IIIB), also known as Sanfilippo syndrome B. This disease is characterized by the lysosomal accumulation and urinary excretion of heparan sulfate.

Gene Name: N-acetylglucosaminidase, alpha

Alternative Symbols: NAG, CMT2V, MPS3B, UFHSD, MPS-IIIB

Protein Name: Alpha-N-acetylglucosaminidase

Molekulargewicht: 81kDa

Gen-ID: 4669

NCBI Accession: NP_000254

UniProt: P54802

Pathways: Glycosaminoglycan Metabolic Process