NAGLU Antikörper (C-Term)

Produktnummer ABIN5517086

Der Kaninchen Polyklonal anti-NAGLU Antikörper (ABIN5517086) detektiert spezifisch NAGLU in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für NAGLU Antikörper (C-Term) (ABIN5517086)

Target: NAGLU (N-Acetylglucosaminidase, alpha (NAGLU))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NAGLU Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-NAGLU Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: NAGLU Antibody - C-terminal region

Sequenz: LEALVDSVAQ GIPFQQHQFD KNVFQLEQAF VLSKQRYPSQ PRGDTVDLAK

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human NAGLU

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP81369-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu NAGLU

Target: NAGLU (N-Acetylglucosaminidase, alpha (NAGLU))

Andere Bezeichnung: NAGLU

Hintergrund:

Background Information: This gene encodes an enzyme that degrades heparan sulfate by hydrolysis of terminal N-acetyl-D-glucosamine residues in N-acetyl-alpha-D-glucosaminides. Defects in this gene are the cause of mucopolysaccharidosis type IIIB (MPS-IIIB), also known as Sanfilippo syndrome B. This disease is characterized by the lysosomal accumulation and urinary excretion of heparan sulfate.

Gene Name: N-acetylglucosaminidase, alpha

Alternative Symbols: NAG, CMT2V, MPS3B, UFHSD, MPS-IIIB

Protein Name: alpha-N-acetylglucosaminidase

Molekulargewicht: 70 kDa

Gen-ID: 4669

NCBI Accession: NP_000254

UniProt: P54802

Pathways: Glycosaminoglycan Metabolic Process