Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TMEM185A in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Rind (Kuh), Hund, Meerschweinchen, Pferd, Ratte und Zebrafisch (Danio rerio).
Produktnummer ABIN5517081
Kurzübersicht für TMEM185A Antikörper (N-Term) (ABIN5517081)
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target
TMEM185A
(Transmembrane Protein 185A (TMEM185A))
Andere Bezeichnung
TMEM185A
Hintergrund
The protein encoded by this gene is predicted to be a transmembrane protein. This gene is best known for localizing to the CpG island of the fragile site FRAXF. The 5' untranslated region of this gene contains a CGG trinucleotide repeat sequence that normally consists of 7-40 tandem CGG repeats but which can expand to greater than 300 repeats. Methylation of the CpG island leads to transcriptional silencing of this gene, but neither the silencing nor an expanded repeat region appear to manifest itself in a clear phenotypic manner. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been defined on the X chromosome.