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COQ6 Antikörper (N-Term)
COQ6
Reaktivität: Human, Ratte, Maus, Kaninchen, Rind (Kuh), Hund, Meerschweinchen, Pferd, Saccharomyces cerevisiae
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN5517062
Produktdetails anti-COQ6 Antikörper
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Target
Alle COQ6 Antikörper anzeigen
COQ6
(Coenzyme Q6, Monooxygenase (COQ6))
Bindungsspezifität
Alle Epitope für COQ6 Antikörper
N-Term
Reaktivität
Alle Reaktivitäten für COQ6 Antikörper
Human, Ratte, Maus, Kaninchen, Rind (Kuh), Hund, Meerschweinchen, Pferd, Saccharomyces cerevisiae
Wirt
Alle Wirte für COQ6 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für COQ6 Antikörper
Polyklonal
Konjugat
Alle Konjugate für COQ6 Antikörper
Dieser COQ6 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für COQ6 Antikörper
Western Blotting (WB)
Sequenz
ILLLEAGPKK VLEKLSETYS NRVSSISPGS ATLLSSFGAW DHICNMRYRA
Homologie
Cow: 93%, Dog: 86%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%, Yeast: 80%
Produktmerkmale
This is a rabbit polyclonal antibody against COQ6. It was validated on Western Blot.
Aufreinigung
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human COQ6
Top Product
Discover our top product COQ6 Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Details zu COQ6
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Target
COQ6
(Coenzyme Q6, Monooxygenase (COQ6))
Andere Bezeichnung
COQ6 (COQ6 Produkte )
Synonyme
CGI10 antikoerper, COQ10D6 antikoerper, 5930427M12Rik antikoerper, AW742344 antikoerper, zgc:153379 antikoerper, coq6 antikoerper, coenzyme Q6, monooxygenase antikoerper, coenzyme Q6 monooxygenase antikoerper, Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial antikoerper, coenzyme Q6 monooxygenase L homeolog antikoerper, COQ6 antikoerper, Coq6 antikoerper, coq-6 antikoerper, coq6 antikoerper, coq6.L antikoerper
Hintergrund
The protein encoded by this gene belongs to the ubiH/COQ6 family. It is an evolutionarily conserved monooxygenase required for the biosynthesis of coenzyme Q10 (or ubiquinone), which is an essential component of the mitochondrial electron transport chain, and one of the most potent lipophilic antioxidants implicated in the protection of cell damage by reactive oxygen species. Knockdown of this gene in mouse and zebrafish results in decreased growth due to increased apoptosis. Mutations in this gene are associated with autosomal recessive coenzyme Q10 deficiency-6 (COQ10D6), which manifests as nephrotic syndrome with sensorineural deafness. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. Alias Symbols: CGI10, COQ10D6 Protein Interaction Partner: SUMO1, UBC, NEDD8, APP, CDK2, ZBTB16, ARSE, Protein Size: 443
Gen-ID
51004
NCBI Accession
NM_182480 , NP_872286
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