COQ6 Antikörper (N-Term)

Produktnummer ABIN5517062

Der Kaninchen Polyklonal anti-COQ6 Antikörper (ABIN5517062) detektiert spezifisch COQ6 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte, Maus, Kaninchen, Rind (Kuh), Hund, Meerschweinchen, Pferd und Saccharomyces cerevisiae.

Kurzübersicht für COQ6 Antikörper (N-Term) (ABIN5517062)

Target: COQ6 (Coenzyme Q6, Monooxygenase (COQ6))

Reaktivität: Human, Ratte, Maus, Kaninchen, Rind (Kuh), Hund, Meerschweinchen, Pferd, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COQ6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-COQ6 Antikörper

Bindungsspezifität: N-Term

Sequenz: ILLLEAGPKK VLEKLSETYS NRVSSISPGS ATLLSSFGAW DHICNMRYRA

Homologie: Cow: 93%, Dog: 86%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%, Yeast: 80%

Produktmerkmale: This is a rabbit polyclonal antibody against COQ6. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human COQ6

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu COQ6

Target: COQ6 (Coenzyme Q6, Monooxygenase (COQ6))

Andere Bezeichnung: COQ6

Hintergrund: The protein encoded by this gene belongs to the ubiH/COQ6 family. It is an evolutionarily conserved monooxygenase required for the biosynthesis of coenzyme Q10 (or ubiquinone), which is an essential component of the mitochondrial electron transport chain, and one of the most potent lipophilic antioxidants implicated in the protection of cell damage by reactive oxygen species. Knockdown of this gene in mouse and zebrafish results in decreased growth due to increased apoptosis. Mutations in this gene are associated with autosomal recessive coenzyme Q10 deficiency-6 (COQ10D6), which manifests as nephrotic syndrome with sensorineural deafness. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Alias Symbols: CGI10, COQ10D6

Protein Interaction Partner: SUMO1, UBC, NEDD8, APP, CDK2, ZBTB16, ARSE,

Protein Size: 443

Gen-ID: 51004

NCBI Accession: NM_182480, NP_872286