FBXL15 Antikörper (N-Term)

Produktnummer ABIN5517039

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch FBXL15 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Ziege, Pferd und Kaninchen.

Kurzübersicht für FBXL15 Antikörper (N-Term) (ABIN5517039)

Target: FBXL15 (F-Box and Leucine-Rich Repeat Protein 15 (FBXL15))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Ziege, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FBXL15 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FBXL15 Antikörper

Bindungsspezifität: N-Term

Sequenz: PPMEPSGGEQ EPGAVRFLDL PWEDVLLPHV LNRVPLRQLL RLQRVSRAFR

Homologie: Cow: 93%, Dog: 100%, Goat: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against FBXL15. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human FBXL15

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu FBXL15

Target: FBXL15 (F-Box and Leucine-Rich Repeat Protein 15 (FBXL15))

Andere Bezeichnung: FBXL15

Hintergrund: FBXL15 is a substrate recognition component of a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of SMURF1, thereby acting as a positive regulator of the BMP signaling pathway. It is required for dorsal/ventral pattern formation and bone mass maintenance and also mediates ubiquitination of SMURF2 and WWP2.

Alias Symbols: FBXO37, Fbl15, JET, PSD

Protein Interaction Partner: HNRNPD, SKP1, ITCH, SMURF2, HECW2, SMURF1, NEDD4L, HECW1, WWP2, WWP1, RBX1, CUL1, NEDD4, HSP90AA1, COPS6, UBC,

Protein Size: 300

Gen-ID: 79176

NCBI Accession: NM_024326, NP_077302

UniProt: Q9H469