FBXL15 Antikörper (N-Term)

Produktnummer ABIN5517039

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch FBXL15 in WB. Er zeigt eine Reaktivität gegenüber Human, Rind (Kuh), Hund, Ziege, Pferd, Maus, Kaninchen und Ratte.

Kurzübersicht für FBXL15 Antikörper (N-Term) (ABIN5517039)

Target: FBXL15 (F-Box and Leucine-Rich Repeat Protein 15 (FBXL15))

Reaktivität: Human, Rind (Kuh), Hund, Ziege, Pferd, Maus, Kaninchen, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FBXL15 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FBXL15 Antikörper

Bindungsspezifität: N-Term

Sequenz: PPMEPSGGEQ EPGAVRFLDL PWEDVLLPHV LNRVPLRQLL RLQRVSRAFR

Homologie: Cow: 93%, Dog: 100%, Goat: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against FBXL15. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human FBXL15

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu FBXL15

Target: FBXL15 (F-Box and Leucine-Rich Repeat Protein 15 (FBXL15))

Andere Bezeichnung: FBXL15

Hintergrund: FBXL15 is a substrate recognition component of a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of SMURF1, thereby acting as a positive regulator of the BMP signaling pathway. It is required for dorsal/ventral pattern formation and bone mass maintenance and also mediates ubiquitination of SMURF2 and WWP2.

Alias Symbols: FBXO37, Fbl15, JET, PSD

Protein Interaction Partner: HNRNPD, SKP1, ITCH, SMURF2, HECW2, SMURF1, NEDD4L, HECW1, WWP2, WWP1, RBX1, CUL1, NEDD4, HSP90AA1, COPS6, UBC,

Protein Size: 300

Gen-ID: 79176

NCBI Accession: NM_024326, NP_077302

UniProt: Q9H469